Download PDF by Jeffrey K. Aronson (Eds.): A worldwide yearly survey of new data and trends in adverse

By Jeffrey K. Aronson (Eds.)

ISBN-10: 0444519866

ISBN-13: 9780444519863

The unintended effects of substances Annual was once first released in 1977. it's been constantly released given that then, as a every year replace to the voluminous encyclopedia Meyler's unintended effects of substances. every one new Annual maintains to supply clinicians and scientific investigators with a competent and important each year survey of latest information and traits within the zone of difficult Drug Reactions and Interactions. a world crew of experts has contributed to the Annuals through identifying significantly from each one year's writing all that's actually new and informative, via seriously studying it, and via pointing to no matter what is deceptive. *Provides a serious every year survey of recent facts and traits *Includes an essay that describes the trendy method of classifying opposed drug reactions *Special experiences during this Annual contain, between different subject matters: Antipsychotic medicines and now-onset diabetes mellitus, Treating bronchial asthma while pregnant, and MMR vaccine and autism

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Additional info for A worldwide yearly survey of new data and trends in adverse drug reactions

Sample text

Here we note that some object to the use of the terms “sensitivity” and “specificity” in this context, because of a supposed lack of gold standards of causality in pharmacovigilance. The question of gold standards is indeed an important point, but it should not be used selectively to shield emerging methods from scientific scrutiny or object to findings that are personally disagreeable. At its extreme, such viewpoints take the form of objecting to the use of adverse events in method testing for which there is no “guarantee” of causality.

He had normal sexual function, and was able to attain and sustain an erection. He described the phenomenon of penile shrinkage as “Whizz-Dick” and stated that all the amfetamine users with whom he was in contact were aware of the phenomenon. He was treated with reassurance and supportive counseling. Reports of koro-like fears of penile shrinkage with amphetamines (7A ) and cannabis (8A , 9A ) are rare. There are no published reports that provide objective evidence that penile shrinkage results from abuse of amphetamines, and the fear is more likely due to altered perception and a poor body image.

Pharmacological basis of adverse drug reactions. In: Speight TM, Holford HG, editors. Avery’s drug treatment. 4th ed. Auckland: Adis International; 1997. p. 261–99. 13. Rawlins MD. Spontaneous reporting of adverse drug reactions. II: Uses. Br J Clin Pharmacol 1988;26:7–11. 14. Lexchin J. Is there still a role for spontaneous reporting of adverse drug reactions? CMAJ 2006;174:191–2. 15. Edwards IR. Spontaneous reporting—of what? Clinical concerns about drugs. Br J Clin Pharmacol 1999;48:138–41. 16.

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A worldwide yearly survey of new data and trends in adverse drug reactions by Jeffrey K. Aronson (Eds.)


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