By P. Marco Fisichella, Fernando A. M. Herbella, Marco G. Patti
every one bankruptcy describes a really particular point of Achalasia by means of its identified specialist. present diagnostic and administration innovations of Achalasia, in addition to the simplified operative techniques with suitable technical concerns, are defined for the explicit objective audience.
The remedy of Achalasia is advanced and typically played in really good tertiary-care centres. The Editors' major target is to render this sickness extra comprehensible and obtainable to citizens, fellows, and experts in either the surgical disciplines (general surgical procedure and thoracic surgical procedure) and in gastroenterology.
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Additional info for Achalasia: Diagnosis and Treatment
Bassotti G, D’Onofrio V, Battaglia E, Fiorella S, Dughera L, Iaquinto G, et al. Treatment with botulinum toxin of octo-nonagerians with oesophageal achalasia: a two-year follow-up study. Aliment Pharmacol Ther. 2006;23(11):1615–9. 19. Goschel H, Wohlfarth K, Frevert J, Dengler R, Bigalke H. Botulinum A toxin therapy: neutralizing and nonneutralizing antibodies – therapeutic consequences. Exp Neurol. 1997;147(1):96–102. 20. Coskun H, Duran Y, Dilege E, Mihmanli M, Seymen H, Demirkol MO. Effect on gastric emptying and 37 21.
Am Surg. 2013;79(1):72–5. 5 Botulinum Toxin for Achalasia Hiroshi Mashimo Introduction Botulinum neurotoxin (BoNT) is one of the most potent toxins known, with a median human lethal dose of 1–2 ng when injected. However, its effect as a neurotoxin has been employed to treat spasms, hyperhidrosis, migraine, and various pain syndromes. It is also widely used for cosmetic treatments. Off-label gastrointestinal uses include treatment of gastroparesis, anal fissures, anismus, sphincter of Oddi dysfunction, and esophageal dysmotility.
Pneumatic balloon dilation. A prospective study with long-term follow-Up. Endoscopy. 2001;33(12):1007–17. Zarate N, Mearin F, Baldovino F, Armengol JR, Malagelada JR. Achalasia treatment in the elderly: is botulinum toxin injection the best option? Eur J Gastroenterol Hepatol. 2002;14(3):285–90. Leyden JE, Moss AC, MacMathuna P. Endoscopic pneumatic dilation versus botulinum toxin injection in the management of primary achalasia. Cochrane Database Syst Rev. 2006;4, CD005046. Campos GM, Vittinghoff E, Rabl C, Takata M, Gadenstatter M, Lin F, et al.
Achalasia: Diagnosis and Treatment by P. Marco Fisichella, Fernando A. M. Herbella, Marco G. Patti