Aging: Modern Theories and Therapies (New Biology) by Joseph Panno PDF

By Joseph Panno

ISBN-10: 0816068461

ISBN-13: 9780816068463

ISBN-10: 1438133642

ISBN-13: 9781438133645

Makes an attempt to appreciate the getting older procedure have generated a number of theories yet few useful remedies. conventional cures deal with age-related illnesses equivalent to melanoma and arthritis yet don't opposite the getting older approach itself. a typical pattern in gerontology is to look for genes that experience a demonstrable impact on lifespan, the so-called sturdiness genes. Many such genes were pointed out, and even if the manipulation of those genes doesn't cease the getting older strategy, they supply many invaluable insights into the mobile mechanisms of getting older. extra lately, curiosity has grew to become to using cloning know-how, stem telephone research, and genetic manipulation on the way to produce an efficient rejuvenation remedy for cells and the physique as an entire.

getting older, Revised version describes the sector of gerontology and the various theories that scientists have constructed through the years to provide an explanation for the age-related adjustments that ensue in approximately all animals.

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Extra resources for Aging: Modern Theories and Therapies (New Biology)

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The first, covering the early years, began around 1870, with the invention of the compound microscope and ended in the 1950s. The second epoch began with the discovery of the DNA double helix in 1952 and extended to the early 1970s. The third epoch began with the introduction of recombinant DNA technology in 1973, ending in the early 1990s. The current epoch, known as the post-genomic era, began with the formation of a genome-sequencing consortium in 1990 and continues to the present day. 4 The History of Gerontology 15 Gerontological research has always been driven by the same questions: Why do people grow old?

The final life span seems to be a balance of all these forces, and given these forces may be the best deal the organism can hope for. There would be no point to nature’s producing a fruit fly that could live a thousand years since their predators eat them all in a matter of days. Scientists might try producing a fly that could live that long, but what in the world would an animal with that level of intelligence do for all that time? This is not just a whimsical point. There is a very strong correlation between longevity and the weight of the brain: “Smart” animals usually live longer than “dumb” animals.

Research focus came in two forms. First, by settling on just four research organisms, different research groups could easily compare results. , mutants have not been identified or characterized). The four organisms chosen by NIA are well characterized genetically, and there are many long- and short-lived mutants available that greatly expedite aging research. Second, aging research shifted from projects aimed at testing one of the many theories of the aging process to a narrower, thus more practical approach involving the search for longevity genes.

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Aging: Modern Theories and Therapies (New Biology) by Joseph Panno

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