By Haboush W., Parshall B. (eds.)
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Additional info for Algebraic Groups and Their Generalizations: Classical Methods, Part 1
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M. Schmitt et al. 3 Immunoproteasome-Specific Inhibitors The immunoproteasome is an inducible proteasome variant primarily expressed in lymphocytes and monocytes, as well as in cells exposed to inflammatory cytokines such as interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α). The immunoproteasome is involved in the production of peptides for major histocompatibility complex-1 (MHC-1). During assembly of the immunoproteasome, the constitutive β1, β2, and β5 subunits are replaced by β1i (PSMB9/LMP2), β2i (PSMB10/LMP-10/ MECL1), and β5i (PSMB8/LMP7), respectively.
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Algebraic Groups and Their Generalizations: Classical Methods, Part 1 by Haboush W., Parshall B. (eds.)